​​​​​​​A place where nurses thrive

At Prisma Health, each of our nurses brings their own unique characteristics to their jobs. But what binds us together is our common commitment to Inspire health. Serve with compassion. Be the difference.​​​​​

RN sign-on bonus currently available

Now is the perfect time to join Prisma Health if you are an experienced RN with a minimum of 1-year acute care experience and licensed in South Carolina! We offer up to a $30,000 sign-on bonus for eligible full-time positions and $10,000 for part-time positions (minimum of 20 hours per week). Prisma Health requires a one-year commitment (we're confident you're going to love working here). We also offer relocation assistance!
 

Our team

Our team is comprised of nearly 29,000 people helping us change thousands of lives for the better every day.
 

A strong legacy of care


As South Carolina’s largest private, non-profit healthcare system, and second-largest private company, we are here to create a better state of health for South Carolinians. Prisma Health is inspired to help people live their healthiest lives. As the most comprehensive integrated healthcare system in South Carolina, we’re on a journey to transform the healthcare experience for our patients and their families.

That’s why our team members are dedicated to living our purpose: Inspire health. Serve with compassion. Be the difference.

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an ambulatory setting under the direction of the physician, Advanced practice provider, or physician resident. Demonstrates clinical competency utilizing evidence based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Adheres to all policies set forth from The Joint Commission, Board of Nursing, Board of Pharmacy, DHEC, CAP, COLA, and other regulatory agencies. Accountabilities Assessment: Collects data and completes nursing assessment utilizing appropriate area and/or age specific standards/policies and tools.  Assesses and recognizes subtle or actual changes in patients' condition and patient response to intervention. Triages patient phone calls and manages...

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an ambulatory setting under the direction of the physician, Advanced practice provider, or physician resident. Demonstrates clinical competency utilizing evidence based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Adheres to all policies set forth from The Joint Commission, Board of Nursing, Board of Pharmacy, DHEC, CAP, COLA, and other regulatory agencies. Accountabilities Assessment: Collects data and completes nursing assessment utilizing appropriate area and/or age specific standards/policies and tools.  Assesses and recognizes subtle or actual changes in patients' condition and patient response to intervention. Triages patient phone calls and manages...

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides direct patient care, education and support to patients in the physician specialty practice setting. Functions as a clinical and community resource, educator and consultant. Utilizes advanced nursing knowledge and experience to influence nursing practice in assigned setting. Bonus This position is bonus eligible, follow this link for details​. Accountabilities • Provides direct patient care in an outpatient physician practice setting. Maintains an advanced knowledge base of disease entities, medications and other treatment options specific to the medical specialty. Assesses and evaluates extensive health history. Evaluates effectiveness of care and makes changes according to predetermined care plan or after consultation with physician. • Performs phone triage accurately by involving physicians when needed. Uses critical thinking skills and advanced knowledge to handle the majority of patient...

Prisma Health Travelers Rest, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Under the direction of a Registered Nurse/Physician, provides nursing care for patients. Assumes responsibility for data collection related to patient status, on-going monitoring, measuring, and documentation of patient responses; provides patient/family instruction. Performs additional patient care functions for which appropriately licensed. Accountabilities Provides patient care based upon individualized plan of care as delegated by the Registered Nurse/Physician including patient's physical, emotional, cultural, spiritual psychosocial, and education needs. Monitors and documents patient status and condition which may include vital signs, drains, dressings, and lab values. Informs appropriate Registered Nurse/Physician of activities performed, observations of patients and their responses, and changes in patient status. Maintain and/or ensures accurate maintenance of patient's medical records and treats...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Performs a variety of services for the Employee Health Program that includes Workers’ Compensation. Accountabilities Assist with pre-employment health evaluations for prospective employees. Performs annual health evaluations on all employees. Maintains Occupational Safety and Health Act (OSHA) records as required. Reviews and follows up on all occupational injury/illness reports. Handles Worker’s Compensation claims. Promotes an environment consistent with the ICP&T Committee findings; to minimize the spread of infectious disease both from employee to patient and from patient to employee. Provides support to the Environment Of Care Committee. Contributes to the maintenance of accurate policies and procedures. Maintains health records in a confidential, accurate and complete manner. Supervisory/Management Responsibility This is a non-management job that will report to a supervisor, manager, director, or...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides direct patient care, education and support to patients in the fellowship trained specialty clinic setting. Functions as a clinical and community resource, educator, and consultant. Able to coordinate and provide care for patients based on detailed treatment protocols initiated by physicians without need of direct physician supervision. Bonus This position is bonus eligible, follow this link for details. Schedule: Monday – Friday, No Weekends, No Call Accountabilities Provides direct patient care in an outpatient specialty setting. Maintains advanced knowledge of diagnoses, medications, and treatment options specific to the specialty. Evaluates effectiveness of care with the physician.  Serves as primary contact for patient/family members (may include 24 hour "on call"). Performs phone triage effectively by involving physicians when needed but uses critical thinking skills and advanced knowledge to...

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary The RN-CVOR has the responsibility of providing direct and indirect nursing care to assigned patients. Also responsible for providing nursing support in the care and preparation of patients undergoing Cardiovascular surgical procedures. Works under the direct and indirect supervision of the Nurse Manager or designee but is independent in the application of CVOR nursing knowledge and skills. Manages clinical situations for which he/she is responsible. Functions as an important member of the surgical team in the operating room and at times, circulates all levels of CVOR and trauma cases. Must be able to take call, including weekends. Bonus This position is bonus eligible, follow this link for details.   Accountabilities * Assessment: Collects patient data and completes required forms with appropriate responses according to unit         standards; identifies patient’s problems/needs and sets priorities;...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Seneca, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary The hospice registered nurse utilizes the nursing process to provide hospice and palliative care to the terminally ill patient, regardless of their age, and supportive care to the patient's family. Adheres to all compliance and policy and procedure requirements of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (The Joint Commission, DHEC). Provides care within the scope of the SC Nursing Practice Act. Bonus This position is bonus eligible. Follow this link for details. Accountabilities Assessment and Planning : The successful Primary RN will assess patient physiological, psychosocial, developmental, environmental needs, and the families' need for supportive care; and...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an outpatient setting. Demonstrates clinical competency utilizing evidence based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit, and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy and procedure requirements of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (JCAHO, DHEC). Provides care within the scope of the SC Nursing Practice Act. The...

Prisma Health Simpsonville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides routine, standardized nursing care for patients under the supervision of the physician. Bonus This position is bonus eligible, follow this link for details. Schedule: Monday – Friday, No Weekends, No Call 1) Assists physicians with examinations, procedures and other activities related to direct patient care. 20% 2) Arranges for patient appointments for diagnostic testing, consults, referrals and admission to hospital. 10% 3) Monitors and maintains stock of medical supplies and proper functioning of equipment. 10% 4) Documents patient's vital statistics and  other encounter data into patient chart and ensures that all required records are in the chart. Obtains brief medical history and chief complaint from patients. 15% 5) Calls in prescriptions for patients according to physician order. 10% 6) Prepares exam rooms with appropriate instruments, supplies and equipment. Cleans exam rooms between...

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary The Sexual Assault Nurse Examiner (SANE RN) provides timely, accurate and compassionate clinical assessment and care, intervention and documentation for patients that have been sexually assaulted. These responsibilities include but are not limited to a forensic examination, prophylaxis for pregnancy and sexually transmitted diseases, photographic documentation, developing a safety plan before patients discharge, referrals for appropriate medical and psychological follow-up and support and participation in legal proceeding while maintaining chain of custody. Collaborates with medical and nursing staff, law enforcement, solicitors, protective services, advocates and other agencies as needed. Serves as resource to hospital staff regarding sexual assault patients while at work. After hire, completion of SANE-A (adolescent/adult) class including the 40 hour didactic training and all clinical requirements associated...

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Easley, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence based practices/research in al areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quaility improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance poilicy, dress code policy, patient confiendtiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Greenville, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Easley, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides clinical direction for all aspects of patient care in an acute inpatient setting, fostering patient/family centered care. Demonstrates clinical competency utilizing evidence-based practices/research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. Incorporates knowledge of safety protocols, cost containment and quality improvement throughout the nursing process. Identifies patient, unit and organizational priorities and incorporates into the nursing process. Adheres to all compliance and policy/procedures of the organization including, but not limited to: licensure renewal, assigned training, employee health screenings, time and attendance policy, dress code policy, patient confidentiality, infection control, medication administration. Demonstrates knowledge of regulatory agency requirements (TJC, DHEC, CMS). Provides care within the scope of the South...

Prisma Health Columbia, SC, USA
Inspire health. Serve with compassion. Be the difference. Job Summary Provides routine, standardized nursing care for patients under the supervision of the physician. Bonus This position is bonus eligible, follow this link for details. Schedule: Monday – Friday, No Weekends, No Call Accountabilities Assessment: Collects data and completes nursing assessment utilizing appropriate area and/or age specific standards/policies and tools.  Assesses and recognizes subtle or actual changes in patients' condition and patient response to intervention. Triages patient phone calls and manages clinical needs within scope of practice. Uses critical thinking skills to guide patient care. - 25% Planning/Outcomes: Collaborates with Physician/ APP/ physician resident to develop plan of care for patient.  Makes appropriate referrals based upon assessment (eg. skin, nutrition, social services). - 15% Implementation: Provides direct care to  patients in a safe, timely, appropriate and cost...