Why Should You Work With MUSC?


At the Medical University of South Carolina (MUSC), we offer nurses a variety of career paths. As a new RN grad or experienced nurse, you can enjoy a supportive team environment, collaborate across disciplines, and help us deliver award-winning patient care to our communities.

Your Input Matters

Nurses are essential to everything we do, and we value your input. Participate in nurse-driven research and help drive practice improvement through our shared governance councils.

Your Role in Patient Care

Our patients and families are the central focus of our care model. You help us build the foundation of patient care in your relationships with your patients, their families, and your colleagues. 

Your Future at MUSC

We want to help you become the patient advocate and leader you're meant to be. MUSC offers professional and personal development opportunities at every stage of your nursing career. 

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The Medical University of South Carolina

Founded in 1824 in Charleston, MUSC is the state’s only comprehensive academic health system, with a mission to preserve and optimize human life in South Carolina through education, research and patient care. Each year, MUSC educates over 3,100 students in six colleges and trains 950+ residents and fellows across its health system. MUSC leads the state in federal and National Institutes of Health and research funding.

As the health care system of the Medical University of South Carolina, MUSC Health is dedicated to delivering the highest-quality and safest patient care while educating and training generations of outstanding health care providers and leaders to serve the people of South Carolina and beyond. In 2024, for the 10th consecutive year, U.S. News & World Report named MUSC Health University Medical Center in Charleston the No. 1 hospital in South Carolina. To learn more about clinical patient services, visit muschealth.org.

MUSC has a total enterprise annual operating budget of $7.1 billion. The 31,000 MUSC members include world-class faculty, physicians, specialty providers, scientists, contract employees, affiliates and care team members who deliver groundbreaking education, research, and patient care.

Full time, Full Time
 
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005406 COL - Labor and Deliver (NMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description **$30,000 Sign on Bonus for Experienced New Hires** Entity/Organization: MUHA (Medical University Hospital Authority/Medical Center) Hours Per Week : 36 Scheduled Work Hours/Shift: 3 twelve-hour shifts per week, 7a-7p, every other weekend. Job Summary/Purpose : Under general supervision, the Registered...

Full time, Full Time
 
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003771 COL - ICU (Intensive Care Unit) (NMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description **$30,000 Sign on bonus for experienced new hires** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required ,...

Full time, Full Time
 
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the Clinical Staff Leader provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired outcomes. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000518 CHS - MICU (Medical ICU) (Main) Pay Rate Type Salary Pay Grade Health-30 Scheduled Weekly Hours 36 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family...

Full time, Full Time
 
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the Forensic Nurse Examiner provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000664 CHS - SAFE (Clincial Forensics Program) (Main) Pay Rate Type Hourly Pay Grade Health-29 Scheduled Weekly Hours 40 Work Shift Job Description Reporting to the SANE Program Coordinator the Forensic Nurse Examiner will provide compassionate and holistic care to victims of sexual assault, intimate partner violence, physical abuse and violent crimes. This is to include obtaining a medical-forensic history, performing a head to toe physical assessment, documentation of physical...

Part time, Part Time
 
MUSC Health SC
Job Description Summary MUSC Health is seeking an Advanced Practice Provider who is interested in providing PRN coverage at a new pediatric urgent care opening in Bluffton, SC. About MUSC Children's Health Pediatric Urgent Care- Bluffton: MUSC Children's Health Pediatric Urgent Care- Bluffton is opening December 2026 and will be located in the MUSC Health Bluffton Medical Pavilion located at 700 Buckwalter Towne Blvd, Bluffton, SC 29910. The pediatric urgent care will be open Monday - Friday from 1pm to 8pm and Saturday - Sunday plus holidays from 11am to 6pm. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC005632 MCP - Bluffton MOB Pay Rate Type Hourly, Salary Pay Grade Health-33 Scheduled Weekly Hours 4 Work Shift Job Description MUSC Health is seeking an Advanced Practice Provider who is interested in providing PRN coverage at a new pediatric urgent care opening in Bluffton, SC. About...

Full time, Full Time
 
MUSC Health Johns Island, SC
Job Description Summary New Clinic-John's Island, South Carolina! In our Pediatric Primary Care clinics, we pride ourselves on fostering a collaborative and supportive environment where every team member plays a critical part in delivering exceptional patient care. As part of our clinical team, you will play a vital role in delivering high quality, patient focused, compassionate care to the patients and families we serve. Responsible for providing quality nursing care while maintaining accountability for the coordination of patient care. Entity University Medical Associates (UMA) Only Employees and Financials Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005083 UMA AMB Maybank Multispecialty Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 40 Work Shift Job Description · Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). · Directs...

Full time, Full Time
 
MUSC Health Mullins, SC
Job Description Summary Sign on Bonus Available for full time employment! Awesome state health benefits and retirement. Up to 6 weeks PAID Parental Leave. Please contact Recruiter Shannon Shaw at 843-674-2694 or shawsh@musc.edu to find out more! Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001611 MAR - Emergency Dept (MMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and...

Part time, Part Time
 
MUSC Health Florence, SC
Job Description Summary Awesome part-time opportunity with full-time benefits. Please contact Recruiter Shannon Shaw at 843-674-2694 or shawsh@musc.edu to find out more! Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003621 FLO - Emergency Dept (FMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 32 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development...

Full time, Full Time
 
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000581 CHS - PACU (Post Anesthesia Care Unit) (ART) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Nights (United States of America) Job Description Hours Per Week : 36 Scheduled Work Hours/Shift: 3–12-hour shifts, M-F (730pm- 8am). Minimal call. Occasional weekend shift to cover a vacation. Job Summary/Purpose : Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at...

Full time, Full Time
 
MUSC Health Florence, SC
Job Description Summary Sign on Bonus Available for full time employment! Awesome state health benefits and retirement. Up to 6 weeks PAID Parental Leave. Please contact Recruiter Shannon Shaw at 843-674-2694 or shawsh@musc.edu to find out more! Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003619 FLO - Surgiday (FMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 40 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and...

Full time, Full Time
 
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the Assistant Nurse Manager provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000421 CHS - Emergency Department - Adult (Main) Pay Rate Type Salary Pay Grade Health-31 Scheduled Weekly Hours 40 Work Shift Nights (United States of America) Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care...

Full time, Full Time
 
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000386 CHS - Surgical Acute Care 6E (ART) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Day (United States of America) Job Description Entity/Organization: MUHA (Medical University Hospital Authority/Medical Center) Hours Per Week : 36 Scheduled Work Hours/Shift: 3 - 12 Hour shifts per week. including some weekends. Job Summary/Purpose: Under general supervision, the Registered Nurse II provides individualized,...

Full time, Full Time
 
MUSC Health Camden, SC
Job Description Summary Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001408 KER - ICU (Intensive Care Unit) (KMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description **$30,000 Sign on Bonus for Experienced New Hires** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a...

Full time, Full Time
 
MUSC Health Columbia, SC
Job Description Summary : Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003769 COL - MedSurg 2nd Floor (NMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description **$30,000 Sign on Bonus for Experienced Hires** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a...

Full time, Full Time
 
MUSC Health Columbia, SC
Job Description Summary : Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003769 COL - MedSurg 2nd Floor (NMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description **$30,000 Sign on Bonus for Experienced Hires** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a...

Full time, Full Time
 
MUSC Health Florence, SC
Job Description Summary Come join our team! Apply today! Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003605 FLO - Step Down (FMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development of nursing diagnoses, outcome identification, planning, implementation of interventions,...

Full time, Full Time
 
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003769 COL - MedSurg 2nd Floor (NMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description **$30,000 Sign on Bonus for Experienced New Hires** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a...

Part time, Part Time
 
MUSC Health Mullins, SC
Job Description Summary Awesome PRN opportunity for an experienced nurse interested in Emergency Services! Eligible to participate in the State Retirement program. Apply today or contact Recruiter Shannon Shaw at shawsh@musc.edu or 843-674-2694 for more information. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC001611 MAR - Emergency Dept (MMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 8 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural,...

Full time, Full Time
 
MUSC Health Mullins, SC
Job Description Summary Sign on Bonus Available for full time employment! Awesome state health benefits and retirement. Up to 6 weeks PAID Parental Leave. Please contact Recruiter Shannon Shaw at 843-674-2694 or shawsh@musc.edu to find out more! Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001611 MAR - Emergency Dept (MMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and...

Full time, Full Time
 
MUSC Health Charleston, SC
Job Description Summary ART 7 West is a specialized 23-bed adult inpatient unit dedicated to the care of patients receiving cellular therapies, including Bone Marrow Transplant, CAR-T, TIL therapy, and other advanced hematologic treatments, as well as those being treated for Malignant Hematology conditions. The team expertly manages patients receiving chemotherapy, immunotherapy, transplantation, and those enrolled in clinical trials, providing close monitoring and personalized care throughout their complex treatment journeys. All nurses complete the National Cancer Institute Collaborative Systemic Therapies Course within their first year to achieve chemotherapy competency, with ongoing opportunities for advanced cancer-specific education. ART 7 West strongly encourages specialty certification in oncology, cellular therapy, medical-surgical nursing, and palliative care, supporting professional growth while maintaining the highest standards of patient-centered care. Entity...

Part time, Part Time
 
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC003713 COL - 4H IICU (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 12 Work Shift Job Description Choose between 24 or 48 hours per 6 weeks Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a certification from an American...