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114 advanced practice jobs found in Columbia, SC

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General Nursing  (103) Intensive Care Unit  (11) Advanced Practice  (9) Cardiology  (3) Operating Room  (2) Surgery  (2)
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MUSC Health
Full time, Full Time
 
MUSC Health Advanced Practice Provider (NP/PA) – Infectious Disease – Columbia, SC
MUSC Health Columbia, SC
Job Description Summary MUSC Health – Columbia Medical Center Downtown is seeking a compassionate and highly skilled Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join our growing Infectious Disease team. This is an exciting opportunity to practice in a collaborative environment focused on delivering exceptional care for patients with complex infectious diseases and conditions. You’ll work alongside a collaborative, multidisciplinary team in a supportive environment that encourages innovation, professional growth, and work-life balance. In this role, you will work closely with Infectious Disease physicians, hospital teams, and multidisciplinary specialists to provide comprehensive inpatient and outpatient care while contributing to improved patient outcomes and community health. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005096 MCP - Columbia Outpt Infectious Disease Pay Rate...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
MUSC Health Advanced Practice Provider (NP/PA) – Cardiovascular APP
MUSC Health Columbia, SC
Job Description Summary MUSC Health Heart & Vascular in Columbia is seeking an Advanced Practice Provider (NP/PA) to join a nationally recognized cardiovascular team providing both inpatient and outpatient care. This is an opportunity to practice alongside leading cardiologists, cardiovascular surgeons, and APPs while caring for a diverse patient population across the Midlands. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001877 MCP - Columbia Heart Laurel St Pay Rate Type Salary Pay Grade Health-33 Scheduled Weekly Hours 40 Work Shift Job Description MUSC Health Heart & Vascular in Columbia is seeking an Advanced Practice Provider (NP/PA) to join a nationally recognized cardiovascular team providing both inpatient and outpatient care. This is an opportunity to practice alongside leading cardiologists, cardiovascular surgeons, and APPs while caring for a diverse patient population...

Oct 05, 2026
MUSC Health
Full time, Full Time
 
MUSC Health Advanced Practice Provider (NP/PA) – Interventional Cardiology APP
MUSC Health Columbia, SC
Job Description Summary MUSC Health is seeking an experienced and highly motivated Nurse Practitioner or Physician Assistant to join the Interventional Cardiology team at Columbia Medical Center. This full-time opportunity combines advanced clinical practice with coordinated inpatient and outpatient care for patients with acute and chronic cardiovascular disease. Working alongside cardiologists, cardiovascular surgeons, cardiology APPs, and multidisciplinary care teams, the APP will evaluate new and established patients, coordinate care across the continuum, and help deliver personalized, evidence-based treatment to patients throughout Columbia and the surrounding communities. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001875 MCP - Columbia Heart Columbia DT Pay Rate Type Salary Pay Grade Health-33 Scheduled Weekly Hours 40 Work Shift Job Description About MUSC Health – Columbia...

Oct 05, 2026
MUSC Health
Full time, Full Time
 
MUSC Health Advanced Practice Provider (NP/PA) | Interventional Cardiology | Columbia, SC
MUSC Health Columbia, SC
Job Description Summary MUSC Health is seeking an experienced and highly motivated Nurse Practitioner or Physician Assistant to join the Interventional Cardiology team at Columbia Medical Center. This full-time opportunity combines advanced clinical practice with coordinated inpatient and outpatient care for patients with acute and chronic cardiovascular disease. Working alongside cardiologists, cardiovascular surgeons, cardiology APPs, and multidisciplinary care teams, the APP will evaluate new and established patients, coordinate care across the continuum, and help deliver personalized, evidence-based treatment to patients throughout Columbia and the surrounding communities. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001875 MCP - Columbia Heart Columbia DT Pay Rate Type Salary Pay Grade Health-33 Scheduled Weekly Hours 40 Work Shift Job Description MUSC Health is seeking an...

Sep 28, 2026
MUSC Health
Full time, Full Time
 
MUSC Health Advanced Practice Provider (APP NP/PA) – Electrophysiology APP
MUSC Health Columbia, SC
Job Description Summary MUSC Health is seeking a compassionate and skilled Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join our growing Electrophysiology team at MUSC Health Heart & Vascular in Columbia, South Carolina. The Electrophysiology APP plays an integral role in the diagnosis, treatment, and ongoing management of patients with cardiac rhythm disorders. Working collaboratively with electrophysiologists, cardiologists, nurses, and other healthcare professionals, the APP provides comprehensive care across outpatient, inpatient, and procedural settings. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001877 MCP - Columbia Heart Laurel St Pay Rate Type Salary Pay Grade Health-33 Scheduled Weekly Hours 40 Work Shift Job Description MUSC Health is seeking a compassionate and skilled Advanced Practice Provider (Nurse Practitioner or Physician Assistant)...

Sep 07, 2026
MUSC Health
Full time, Full Time
 
Advanced Practice Provider (NP/PA) - Heart Failure ICU - Columbia SC
MUSC Health Columbia, SC
Job Description Summary MUSC Health – Columbia Medical Center Downtown is seeking a dedicated and skilled Advanced Practice Provider (APP) to join our Heart Failure ICU team within the nationally recognized MUSC Health Heart and Vascular Division for inpatient nights. This full-time position offers the opportunity to provide both inpatient and outpatient care to patients with advanced and complex cardiac disease, with a particular focus on heart failure. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC001875 MCP - Columbia Heart Columbia DT Pay Rate Type Hourly, Salary Pay Grade Health-33 Scheduled Weekly Hours 40 Work Shift Job Description MUSC Health – Columbia Medical Center Downtown is seeking a dedicated and skilled Advanced Practice Provider (APP) to join our Heart Failure ICU team within the nationally recognized MUSC Health Heart and Vascular Division for inpatient nights. This...

Jul 27, 2026
MUSC Health
Full time, Full Time
 
Advanced Practice Provider (NP/PA) – Non-Invasive Cardiology APP
MUSC Health Columbia, SC
Job Description Summary The Medical University of South Carolina (MUSC Health) is seeking a compassionate and highly skilled Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join the Non-Invasive Cardiology program at MUSC Health Columbia Medical Center Downtown. This role focuses on providing comprehensive, patient-centered cardiovascular care with an emphasis on the evaluation, diagnosis, and medical management of cardiovascular conditions through non-invasive cardiac testing and clinical assessment. The APP will work within a multidisciplinary heart and vascular team to evaluate and manage patients across the continuum of care, including both inpatient and outpatient settings. Responsibilities include conducting comprehensive cardiovascular assessments, ordering and interpreting non-invasive cardiac diagnostic tests, and developing evidence-based treatment plans. The provider will collaborate closely with cardiologists, nurses, and other healthcare...

Jul 27, 2026
MUSC Health
Part time, Part Time
 
MUSC Health Advanced Practice Provider (APP NP/PA) – Structural Heart APP (PRN)
MUSC Health Columbia, SC
Job Description Summary MUSC Health is seeking a highly motivated and collaborative Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join our Structural Heart Program on a PRN basis. This role offers the opportunity to work with a dynamic, multidisciplinary cardiovascular team caring for patients with complex valvular and structural heart disease. In this position, you will support procedural and clinical care across the continuum, contributing to innovative, life-changing therapies such as TAVR, MitraClip, and other transcatheter interventions. The practice is part of MUSC Health’s greater Heart & Vascular Center, which provides compassionate care and advanced treatment to patients across South Carolina. MUSC Health Heart & Vascular Center has received the Society of Thoracic Surgeons’ 3-star rating 20 years in a row, is accredited by the Society of Chest Pain Centers, and is a BlueCross BlueShield of South Carolina BlueDistinction® Center for...

Jul 27, 2026
MUSC Health
Full time, Full Time
 
MUSC Health Advanced Practice Provider (APP NP/PA) – Cognitive & Behavioral Neurology (SCAN)
MUSC Health Columbia, SC
Job Description Summary MUSC Health is seeking a compassionate and skilled Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join the South Carolina Alzheimer's Network (SCAN) within the Cognitive & Behavioral Neurology Division. In this role, you will provide specialized care for patients with Alzheimer's disease and other cognitive disorders while helping improve access to innovative treatments, research opportunities, and coordinated long-term care. You will work alongside a collaborative interdisciplinary team dedicated to delivering comprehensive dementia care and supporting patients, caregivers, and referring providers throughout the treatment journey. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005692 MCP - Midlands SCAN Pay Rate Type Hourly, Salary Pay Grade Health-33 Scheduled Weekly Hours 40 Work Shift Job Description MUSC Health is seeking a...

Jul 27, 2026
MUSC Health
Full time, Full Time
 
Nurse Practitioner or Physician Assistant - Internal Medicine Primary Care
MUSC Health Columbia, SC
Job Description Summary The successful applicant will be an Advanced Practice Provider interested in working full-time in the care of patients in primary care. This APP will have 9 half-day clinic sessions per week, with a combination of sessions focused on a chronic care panel of patients and sessions focused on Acute patient visits. This position is located in both our University Internal Medicine Patient Centered Medical Home practice in Rutledge Tower on the MUSC campus in downtown Charleston as well as our MUSC Health East Cooper Internal Medicine practice at 1600 Midtown Ave. in Mt. Pleasant. These are both busy and thriving practices that include providers specializing in General Internal Medicine and Geriatrics. Entity University Medical Associates (UMA) Only Employees and Financials Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000969 COM DOM GIM Internal Medicine CC Pay Rate Type Salary Pay Grade Health-33 Scheduled Weekly...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Employee Health
MUSC Health Columbia, SC
Job Description Summary The Employee Health nurse provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide patient/family centered care using the nursing process and focusing on the physical, emotional, spiritual, cultural, religious, and environmental needs. This includes providing for the assessment, development of nursing diagnoses, outcome identification, planning, implementation of interventions, coordination of care, health teaching and promotion and evaluation of goals and interventions consistent with the policies of MUSC. Maintains a safe, therapeutic, and healing environment through ensuring patient privacy and responsive, respectful, accepting, and professional behavior. Demonstrates the ability...

Jul 27, 2026
MUSC Health
Part time, Part Time
 
Cardiothoracic CRNA (PRN) | Very Competitive Compensation | MUSC Health Columbia Medical Center | Columbia, SC
MUSC Health Columbia, SC
Job Description Summary MUSC Health – Columbia Medical Centers are seeking Certified Registered Nurse Anesthetists to join our growing practice in Columbia, SC on a PRN basis. The provider will work in collaboration with a dedicated Anesthesia Care Team comprised of experienced CRNAs and board-certified anesthesiologists. This role will focus primarily on major vascular, cardiac, and thoracic anesthesia; but may include general surgery and ASC cases as well. Entity MUSC Community Physicians (MCP) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC001869 MCP - Columbia Anesthesia Pay Rate Type Hourly Pay Grade Health-36 Scheduled Weekly Hours 40 Work Shift Job Description MUSC Health – Columbia Medical Centers are seeking Certified Registered Nurse Anesthetists to join our growing practice in Columbia, SC on a PRN basis. The provider will work in collaboration with a dedicated Anesthesia Care Team comprised of experienced CRNAs and...

Jul 27, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - CSR
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003726 COL - Cardiac Surgery Recovery (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *$18,000 sign on bonus for experienced new hires* Minimum Training and Education : Associate’s Degree in Nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required, either a...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - STU- Weekend Work Plan Days
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000776 COL - 6H STU (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *** $30,000 Sign-On Bonus Available to New Hires w/Experience! *** Work 36 hours and get paid for 48 Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. At least one year of experience as a Registered Nurse. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - STU
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000776 COL - 6H STU (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *** $30,000 Sign-On Bonus Available to New Hires w/Experience! *** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a...

Oct 12, 2026
MUSC Health
Part time, Part Time
 
Registered Nurse II- PRN Nights -STU
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC000776 COL - 6H STU (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 12 Work Shift Nights (United States of America) Job Description Choose from 24 or 48 hours per 6 weeks Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Critical Care Resident RN
MUSC Health Columbia, SC
Job Description Summary Goal: This program’s goal is to foster nurse growth and critical care skills in a team-oriented environment. Details of the Program The Critical Care Residency Program is a supervised rotational residency tailored to the needs of the New Graduate Nurse. Unit details below 4 Heart Intermediate Intensive Care Unit (4H IICU) A 16-bed unit that provides continuous hemodynamic and cardiac monitoring; comprehensive medical management of complex conditions including LVADs, trach vents, neurological and gastrointestinal disorders, alcohol withdrawal (CIWA), and fluid and electrolyte imbalances; and the provision of peritoneal dialysis. The IICU team emphasizes early recognition and timely intervention for clinical deterioration and works collaboratively with critical care and multidisciplinary services to stabilize patients, prevent escalation to higher levels of care, and facilitate safe transitions to lower acuity settings when appropriate. Medical...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Critical Care Resident RN
MUSC Health Columbia, SC
Job Description Summary Goal: This program’s goal is to foster nurse growth and critical care skills in a team-oriented environment. Details of the Program The Critical Care Residency Program is a supervised rotational residency tailored to the needs of the New Graduate Nurse. Unit details below 4 Heart Intermediate Intensive Care Unit (4H IICU) A 16-bed unit that provides continuous hemodynamic and cardiac monitoring; comprehensive medical management of complex conditions including LVADs, trach vents, neurological and gastrointestinal disorders, alcohol withdrawal (CIWA), and fluid and electrolyte imbalances; and the provision of peritoneal dialysis. The IICU team emphasizes early recognition and timely intervention for clinical deterioration and works collaboratively with critical care and multidisciplinary services to stabilize patients, prevent escalation to higher levels of care, and facilitate safe transitions to lower acuity settings when appropriate. Medical...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - CICU - Days
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC005290 COL - CICU (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *** $30,000 Sign-On Bonus Available to New Hires w/Experience! *** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a...

Oct 12, 2026
MUSC Health
Part time, Part Time
 
Registered Nurse II- Medsurg - NE PRN
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse provides individualized, goal-directed patient care to families and patients at a competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ PRN Cost Center CC003769 COL - MedSurg 2nd Floor (NMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 12 Work Shift Job Description Choose between 24 or 48 hours per 6 weeks Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS) required , either a certification from an...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse - ED Days
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003725 COL - Emergency Department (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *** $30,000 Sign-On Bonus Available to New Hires w/Experience! *** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS)...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse - ED - Nights
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003725 COL - Emergency Department (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *** $30,000 Sign-On Bonus Available to New Hires w/Experience! *** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS)...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse - ED - Nights
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003725 COL - Emergency Department (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *** $30,000 Sign-On Bonus Available to New Hires w/Experience! *** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS)...

Oct 12, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse - ED - Nights
MUSC Health Columbia, SC
Job Description Summary Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC003725 COL - Emergency Department (DMC) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Job Description *** $30,000 Sign-On Bonus Available to New Hires w/Experience! *** Minimum Training and Education : Associate degree in nursing. Bachelor’s degree preferred. Required Licensure, Certifications, Registrations : Licensure as a registered nurse by the South Carolina Board of Nursing or a compact state. Current Basic Life Support (BLS)...

Oct 12, 2026
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