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202 rn jobs found in Spartanburg, SC

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General Nursing  (190) Emergency Services  (8) Intensive Care Unit  (8) Neurology  (8) Operating Room  (8) Cardiology  (7)
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Spartanburg Regional Healthcare System
Clinical RN II
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements SIGN ON BONUS $10,000.00 Eligible Experienced RN We are hiring a Registered Nurse to join our team in Surgery! Full-Time; 11:00am to 7:00pm With call/call pay When you combine your Passion to be the best OR Registered Nurse with a career, you - re making the decision to share your compassion, empathy, and desire to serve with heart. It takes a special person to give your time in service to others in providing the best possible patient care. Spartanburg Regional Perioperative department is a Level 1 Trauma Center that puts our patient needs first by giving service in Excellence. The decision to connect your enthusiasm and desire to assist in the care of patients from all walks of life can be the start of limitless possibilities. By joining Spartanburg Regional Healthcare System, you are choosing to be challenged and grow by: By continuous preparedness though state of the art OR training and technology at a highly respected...

Mar 18, 2026
Spartanburg Regional Healthcare System
RN Surgery
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements SIGN ON BONUS $10,000.00 Eligible Experienced RN We are hiring a Registered Nurse to join our Surgery team! Full-Time; 11:00am to 7:00pm With call/call pay When you combine your Passion to be the best OR Registered Nurse with a career, you - re making the decision to share your compassion, empathy, and desire to serve with heart. It takes a special person to give your time in service to others in providing the best possible patient care. Spartanburg Regional Perioperative department is a Level 1 Trauma Center that puts our patient needs first by giving service in Excellence. The decision to connect your enthusiasm and desire to assist in the care of patients from all walks of life can be the start of limitless possibilities. By joining Spartanburg Regional Healthcare System, you are choosing to be challenged and grow by: By continuous preparedness though state of the art OR training and technology at a highly respected...

Mar 18, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Weekend Staffing Team - Level II - Oncology
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Accepting new grad and experienced RNs! You may be eligible for a sign on bonus : $7,500 for new grads or $10,000 for experienced RNS! Relocation bonus, NCLEX reimbursement, and student loan assistance also available to eligible applicants. Apply today to learn more! Unit Summary Welcome to SMC's Inpatient Oncology unit! Our 30-bed unit, located on the first floor of Gibbs Cancer Center, is dedicated to providing exceptional care. Each room is private and includes accommodations for family members, ensuring a supportive environment. We offer specialized rooms with negative/positive pressure airflow and facilities for patients receiving radiation implants. A family room is available for confidential consultations with healthcare teams, and a kitchen is provided for families. Our primary focus is on patients with end-stage illnesses, end-of-life needs, cancer, and hematologic diagnoses. We also provide care to patients...

Mar 18, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Cardiac Cath Lab
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Join our Cardiac Cath Lab Team at Spartanburg Regional Healthcare System! Location: Spartanburg, SC Shift: 8 am – 4:30 pm Ready to elevate your career and make a profound impact on patients' lives? Step into an exhilarating role with our dynamic Cath Lab team at Spartanburg Regional Healthcare System, where your expertise as a Registered Nurse (RN) – Cardiac Cath Lab will be put to the test in a fast-paced, high-stakes environment. Here, you'll not only provide therapeutic patient care but also be a key player in advancing our mission and goals. Your role is integral in fostering our culture of excellence, ensuring that every patient receives top-notch care, and supporting the professional development of your fellow team members. Unit Description Our Cath Lab is at the forefront of minimally invasive interventional cardiology, where innovation meets patient care. You will be part of a team performing a variety of cutting-edge...

Mar 18, 2026
Spartanburg Regional Healthcare System
RN - ICU - Spartanburg Hospital For Restorative Care-NIGHTS
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Unit Details: TU-ICU Nurse to Patient Ratio-1:2 Beds: 3 Case Types: Drips, Cardiac, Renal Wounds, Trauma Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage and support Spartanburg Regional Healthcare System's...

Mar 18, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Progressive Coronary Care Unit (5 Heart)
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Unit Description 5 Heart is a 32-bed cardiac stepdown unit for cardiac medical patients who need special heart monitoring due to chest pain or congestive heart failure, or after a heart catheterization or angioplasty and placement of a stent. This unit will also sometimes take post-surgical patients. Typical nurse to patient ratio is 1:3, or 1:4, with a free charge available on all shifts. This is a great unit for anyone who enjoys learning a lot within a broad patient base and working in a teamwork focused environment. Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates...

Mar 18, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Progressive Coronary Care Unit (5 Heart)
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Unit Description 5 Heart is a 32-bed cardiac stepdown unit for cardiac medical patients who need special heart monitoring due to chest pain or congestive heart failure, or after a heart catheterization or angioplasty and placement of a stent. This unit will also sometimes take post-surgical patients. Typical nurse to patient ratio is 1:3, or 1:4, with a free charge available on all shifts. This is a great unit for anyone who enjoys learning a lot within a broad patient base and working in a teamwork focused environment. Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates...

Mar 18, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - OB Antepartum
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Unit Description Spartanburg Medical Center is a Baby-Friendly acute care hospital with a Level III NICU and an OB Laborist program. Our prestigious Labor and Delivery unit is One of the 5 Level III perinatal centers in our region, delivering roughly 250 babies per month. We have 6 Triage beds, 14 LDRs with the potential for 16. This team of dedicated professionals is defined by teamwork and a passion for the patients they serve. Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps,...

Mar 18, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Labor & Delivery
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Unit Description Spartanburg Medical Center is a Baby-Friendly acute care hospital with a Level III NICU and an OB Laborist program. Our prestigious Labor and Delivery unit is One of the 5 Level III perinatal centers in our region, delivering roughly 250 babies per month. We have 6 Triage beds, 14 LDRs with the potential for 16. This team of dedicated professionals is defined by teamwork and a passion for the patients they serve. Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps,...

Mar 18, 2026
Spartanburg Regional Healthcare System
PRN-RN Tier 2 - Cardiology
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Position Summary The Registered Nurse provides nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures and guidelines. The R.N. demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation and outcomes. The R.N. demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways, team dynamics, hospital systems, and serves as a resource for support associates. The R.N. will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System’s culture, Mission, Vision, and values. Associates are encouraged to support Spartanburg Regional Healthcare System’s involvement in the community we serve. Under supervision of a physician or Nurse Practitioner, the R.N. demonstrates thorough knowledge of treatment and...

Mar 18, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Cardiac Cath Lab
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Join our Cardiac Cath Lab Team at Spartanburg Regional Healthcare System! Location: Spartanburg, SC Shift: 4-10s, 11 am - 9 pm Ready to elevate your career and make a profound impact on patients' lives? Step into an exhilarating role with our dynamic Cath Lab team at Spartanburg Regional Healthcare System, where your expertise as a Registered Nurse (RN) – Cardiac Cath Lab will be put to the test in a fast-paced, high-stakes environment. Here, you'll not only provide therapeutic patient care but also be a key player in advancing our mission and goals. Your role is integral in fostering our culture of excellence, ensuring that every patient receives top-notch care, and supporting the professional development of your fellow team members. Unit Description Our Cath Lab is at the forefront of minimally invasive interventional cardiology, where innovation meets patient care. You will be part of a team performing a variety of...

Feb 25, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Home Health PRN
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements We are hiring a Registered Nurse to join our Home Health team working PRN! PRN Days; 8:30am - 5:00pm At Spartanburg Regional Home Health, we are proud of our skilled, caring, trustworthy and compassionate Home Health experts. Our clinicians visit patient homes to deliver customized, physician-prescribed care after a hospital stay, illness or injury to rehabilitate and achieve optimal level of independence. Home Health is an alternative to repeated hospitalizations or an extended hospital stay. Nurses and medical professionals work closely with primary care physicians and ensure patients are receiving optimum care tailored to individual needs. Our Registered Nurses enjoy autonomy while caring for patients in their home environment. The team works with a wide variety of cases such as: Wound Care, Cardiac, Diabetes, Endocrine, Musculosketal, Pressure Ulcers, Infusion, etc. The Registered Nurse provides skilled nursing services within...

Feb 25, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Hospice House PRN
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements We are hiring a Registered Nurse to join our Hospice House team working PRN! PRN; Days or Nights as needed Spartanburg Regional Hospice Home is an inpatient facility for patients under hospice care. The Spartanburg Regional Hospice Home is fully staffed 24/7 to provide care for patients and families. Hospice provides a team approach for expert medical care, symptom management, and emotional and spiritual support tailored to each patient. Our RNs work together within a multidisciplinary team to provide our patients with the best care. Our teams include: Attending physician, RN/Case Manager, Hospice Aide, Medical Social Worker, Chaplain, etc. The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of...

Feb 25, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Hospice House PRN Nights
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements We are hiring a Registered Nurse to join our Hospice House team working PRN! PRN Nights; 7p to 7a Spartanburg Regional Hospice Home is an inpatient facility for patients under hospice care. The Spartanburg Regional Hospice Home is fully staffed 24/7 to provide care for patients and families. Hospice provides a team approach for expert medical care, symptom management, and emotional and spiritual support tailored to each patient. Our RNs work together within a multidisciplinary team to provide our patients with the best care. Our teams include: Attending physician, RN/Case Manager, Hospice Aide, Medical Social Worker, Chaplain, etc. The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the...

Feb 25, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN)- 3 Main Acute Care Med Surg (Nights)
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage and support Spartanburg Regional Healthcare System's involvement in the communities we serve. Minimum Requirements Education Graduate of an approved / accredited...

Feb 11, 2026
Spartanburg Regional Healthcare System
RN-Medsurg MB NIGHTS-Part-Time
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Unit Details: Mary Black 3 Tower-Multi-Specialty MedSurg Nurse to Patient Ratio- 1:4 or 1:5 depending on acuity Beds: 22 Case types: General Medical Surgical, Pneumonia, Diabetes, Sickle Cell, Cellulitis Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and...

Feb 11, 2026
Spartanburg Regional Healthcare System
RN-Medsurg MB NIGHTS
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Unit Details: Mary Black 3 Tower-Multi-Specialty MedSurg Nurse to Patient Ratio- 1:4 or 1:5 depending on acuity Beds: 22 Case types: General Medical Surgical, Pneumonia, Diabetes, Sickle Cell, Cellulitis Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and...

Feb 11, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Home Health
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements SIGN ON BONUS $10,000.00 Eligible Experienced RN We are hiring a Registered Nurse to join our Home Health team! Full-Time; 9:00am - 5:00 pm At Spartanburg Regional Home Health, we are proud of our skilled, caring, trustworthy and compassionate Home Health experts. Our clinicians visit patient homes to deliver customized, physician-prescribed care after a hospital stay, illness or injury to rehabilitate and achieve optimal level of independence. Home Health is an alternative to repeated hospitalizations, or an extended hospital stay. Nurses and medical professionals work closely with primary care physicians and ensure patients are receiving optimum care tailored to individual needs. Our Registered Nurses enjoy autonomy while caring for patients in their home environment. The team works with a wide variety of cases such as: Wound Care, Cardiac, Diabetes, Endocrine, Musculosketal, Pressure Ulcers, Infusion, etc. The average length of...

Feb 11, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) Home Health
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements SIGN ON BONUS $10,000.00 Eligible Experienced RN We are hiring a Registered Nurse to join our Home Health team! Full-Time; 8:30am - 5:00pm At Spartanburg Regional Home Health, we are proud of our skilled, caring, trustworthy and compassionate Home Health experts. Our clinicians visit patient homes to deliver customized, physician-prescribed care after a hospital stay, illness or injury to rehabilitate and achieve optimal level of independence. Home Health is an alternative to repeated hospitalizations or an extended hospital stay. Nurses and medical professionals work closely with primary care physicians and ensure patients are receiving optimum care tailored to individual needs. Our Registered Nurses enjoy autonomy while caring for patients in their home environment. The team works with a wide variety of cases such as: Wound Care, Cardiac, Diabetes, Endocrine, Musculosketal, Pressure Ulcers, Infusion, etc. The average length of...

Feb 11, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN) - Home Health
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements SIGN ON BONUS $10,000.00 Eligible Experienced RN We are hiring a Registered Nurse to join our Home Health team! Full-Time; 8:30 am-5:00 pm At Spartanburg Regional Home Health, we are proud of our skilled, caring, trustworthy and compassionate Home Health experts. Our clinicians visit patient homes to deliver customized, physician-prescribed care after a hospital stay, illness or injury to rehabilitate and achieve optimal level of independence. Home Health is an alternative to repeated hospitalizations or an extended hospital stay. Nurses and medical professionals work closely with primary care physicians and ensure patients are receiving optimum care tailored to individual needs. Our Registered Nurses enjoy autonomy while caring for patients in their home environment. The team works with a wide variety of cases such as: Wound Care, Cardiac, Diabetes, Endocrine, Musculosketal, Pressure Ulcers, Infusion, etc. The average length of...

Feb 11, 2026
Spartanburg Regional Healthcare System
Tier 2 PRN-Registered Nurse (RN) - Cardiac Cath Lab - Holding Room
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Join Our Energetic Team at Spartanburg Regional Healthcare System as a PRN-Registered Nurse – Cardiac Cath Lab - Holding Room! Position Summary Are you ready to make a meaningful impact in patient care while working with an enthusiastic and supportive team? As a PRN-Registered Nurse at Spartanburg Regional Healthcare System, you will utilize your comprehensive knowledge of therapeutic patient care, patient advocacy, and teamwork. Collaborate with leadership to embody and advance our culture, Vision, Mission, and goals. Join us and be part of a professional practice program where every key responsibility builds on your expertise and dedication. Unit Description Our Cardiac Cath Lab is the heart of minimally invasive interventional cardiology. Here, you will be involved in: Diagnostic Testing: Identify heart conditions like blockages. Interventional Procedures: Atherectomy Coronary angioplasty Chronic total occlusion (CTO)...

Feb 04, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN)- MB Ortho 3
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements ***Sign On Bonus: New Grads - Med-Surg $7,500, and Experienced RNs $10,000*** New graduates and experienced RN's are encouraged to apply. Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage and support Spartanburg...

Feb 04, 2026
Spartanburg Regional Healthcare System
Clinical RN II (RN)- MB Ortho
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Job Description ***Sign On Bonus: New Grads - Med-Surg $7,500, and Experienced RNs $10,000*** New graduates and experienced RN's are encouraged to apply. Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage...

Feb 04, 2026
Spartanburg Regional Healthcare System
Registered Nurse (RN)- MB Ortho
Spartanburg Regional Healthcare System Spartanburg, SC, USA
Description Job Requirements Position Summary The Acute Care Registered Nurse (RN) provides inpatient nursing care to patients in compliance with the SC Nurse Practice Act and organization protocols, policies, procedures, and guidelines. The RN demonstrates clinical competency utilizing evidence-based practices and research in all areas of the nursing process: assessment, planning, implementation, evaluation, and outcomes. The RN demonstrates thorough knowledge of therapeutic patient care, patient advocacy, clinical pathways/care maps, team dynamics, hospital systems, and serves as a resource for support associates. The RN will collaborate with leadership in developing and implementing the Spartanburg Regional Healthcare System's culture, Mission, Vision, and Values. Associates are encouraged to engage and support Spartanburg Regional Healthcare System's involvement in the communities we serve. Minimum Requirements Education Graduate of an approved / accredited...

Feb 04, 2026
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