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39 advanced practice jobs found in Charleston, SC

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General Nursing Charleston, SC advanced practice
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Operating Room  (24) Cardiology  (8) Oncology  (8) Advanced Practice  (3) Intensive Care Unit  (3) Neurology  (3)
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MUSC Health
Full time, Full Time
 
Registered Nurse-Burn Clinic
MUSC Health Charleston, SC
Job Description Summary MUSC Health Burn Surgery at Rutledge Tower, located in Rutledge Tower in Charleston, provides specialized, comprehensive care for patients with burn injuries and complex wounds. This outpatient clinic is part of MUSC Health, a nationally recognized academic medical center known for advanced surgical care and innovative treatment approaches. The clinic is staffed by a multidisciplinary team of fellowship-trained burn and reconstructive surgeons, along with advanced practice providers and support specialists, delivering expert care for both adult and pediatric patients. Services include evaluation and treatment of acute and chronic burns, wound care management, and reconstructive surgical planning. Patients benefit from MUSC Health’s leading-edge burn program, which emphasizes personalized treatment plans, minimally invasive techniques when appropriate, and access to the latest research and clinical advancements in burn care. Entity Medical University...

Jun 15, 2026
Roper St. Francis Healthcare
Registered Nurse (RN) or Electrophysiology Technologist - Electrophysiology (EP) Lab - Roper Hospital
Roper St. Francis Healthcare Charleston, SC
ROPRSFUSR270984EXTERNALENUS Thank you for considering a career at Roper St. Francis Healthcare! Shift Hours: 7:00am - 5:30pm; four 10-hour shifts per week. Rotating day off. Manager prefers prior EP, Cath, ED, ICU, or procedural experience Summary of Primary Function Delivers patient care utilizing the nursing process through data collection and assessment, identifies and determines the priority of patient’s problems/needs, and evaluates the process and outcome of nursing care; coordinates, provides and directs patient teaching activities and coordinates the care provided by health team members.                                                                                                                                                                            Essential Job Functions In collaboration with the interdisciplinary care team, conducts initial and ongoing patient assessment, analyzes assessment data, creates a plan of care, implements treatment and...

Jul 04, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse I (New Graduate) - 7E Medical Acute Care
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the Registered Nurse I (New Graduate) assists at the advanced beginner level in providing individualized, goal directed nursing care to patients and families utilizing principles and practices of the nursing process; interacts with other members of the health care team to achieve desired outcomes. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000514 CHS - MedSurg 7E (Main) Pay Rate Type Hourly Pay Grade Health-27 Scheduled Weekly Hours 36 Work Shift Rotating (United States of America) Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide...

Jun 29, 2026
MUSC Health
Part time, Part Time
 
Registered Nurse I ( New Grad ) - 7A Family Medicine
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the Registered Nurse I assists at the advanced beginner level in providing individualized, goal directed nursing care to patients and families utilizing principles and practices of the nursing process; interacts with other members of the health care team to achieve desired outcomes. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000442 CHS - Family Medicine - 7A (Main) Pay Rate Type Hourly Pay Grade Health-27 Scheduled Weekly Hours 36 Work Shift Rotating (United States of America) Job Description Provides nursing care to patients using the nursing process (assessment, planning, implementation, and evaluation). Directs and leads other assigned team members and collaborates with multidisciplinary team members to provide age/developmentally appropriate care in accordance with nursing standards of care and practice. Provide...

Jun 29, 2026
MUSC Health
Part time, Part Time
 
RN Charge - Main OR
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the RN - Charge Nurse manages the daily operational oversight to ensure effective delivery of patient care. This position interacts with members of the healthcare team to achieve desired results. The RN – Charge Nurse consistently models excellence in patient care and contributes to unit leadership. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000567 CHS - OR - Main (Main) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 32 Work Shift Day (United States of America) Job Description Hours per week: 32 Scheduled Work Hours/Shift: Weekends 6:00 am- 6:00pm Fair Labor Standards Act Status: Hourly Job Summary/Purpose : Under general supervision, the RN - Charge Nurse manages the daily operational oversight to ensure effective delivery of patient care. This position interacts with members of the healthcare...

Jun 10, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - 10E Orthopedics
MUSC Health Charleston, SC
Job Description Summary MUSC’s Orthopedic Unit is located on 10 East in the Main Hospital in beautiful downtown Charleston. 10 East is a 20 bed acute care, post-operative unit, specializing in Orthopedic and Urology surgeries. Our patients seek us out for our expertise in adult reconstruction, total joint replacement, ortho trauma, ortho oncology, and urologic procedures. MUSC’s Joint Replacement program has received the Join Commission Advanced Certification for Total Hip and Knee Replacement and the Joint Commission Gold Seal Certification for Total Shoulder Replacement. The Orthopedic unit was awarded the NAON Nursing Excellence (ONE) Award acknowledging our commitment to professionalism in nursing practice through exemplary care for patient and achievement in quality outcomes. We are always looking for qualified, compassionate care team members to join our team. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular...

Jun 10, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - SJCH Peds Critical Care Unit
MUSC Health Charleston, SC
Job Description Summary Registered Nurse II Entity/Organization: MUHA (Medical University Hospital Authority/Medical Center) Job Summary/Purpose: Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Minimum Training and Education: Bachelor of Nursing degree preferred. RN staff hired on or after July 1, 2013 with an Associate or Diploma degree in nursing are required to be enrolled in an accredited BSN program within two years and successfully obtain a BSN degree within four years of the RN hire or reclassification date. Refer to policy A141 for more details. A minimum of one year of work experience as a registered nurse required. Required Licensure, Certifications, Registrations: Licensure as a...

Jun 10, 2026
MUSC Health
Full time, Full Time
 
UNIV - Registered Nurse III - Department of Medicine: Division of Cardiology
MUSC Health Charleston, SC
Job Description Summary Primary RN research coordinator for Phase I/II/III drug trials and early phase medical devices within all subcategories of Cardiology. Provides leadership and direction to professional and paraprofessional nursing personnel in direct patient care, patient and student education and counseling, coordination of clinical and research services for patients and their families. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type​ Research Grant Cost Center CC000966 COM DOM CARD General CC Pay Rate Type Salary Pay Grade University-08 Pay Range 69,764.00 - 99,421.00 - 129,077.000 Scheduled Weekly Hours 40 Work Shift Job Description Job Duties: 35% - Act as Primary Coordinator for Phase I/II drug trials and early phase medical device trials. Coordinate and/or deliver nursing care (labs, medications, questionnaires, nursing physical assessment and vital signs, patient and family...

Jun 10, 2026
MUSC Health
Full time, Full Time
 
RN Charge - Main Operating Room
MUSC Health Charleston, SC
Job Description Summary Under general supervision, the RN - Charge Nurse manages the daily operational oversight to ensure effective delivery of patient care. This position interacts with members of the healthcare team to achieve desired results. The RN – Charge Nurse consistently models excellence in patient care and contributes to unit leadership. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000567 CHS - OR - Main (Main) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Day (United States of America) Job Description Hours per week: 36 Scheduled Work Hours/Shift: Weekends 6:00 am- 6:00pm Fair Labor Standards Act Status: Hourly Job Summary/Purpose : Under general supervision, the RN - Charge Nurse manages the daily operational oversight to ensure effective delivery of patient care. This position interacts with members of the healthcare...

Jun 10, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - 6E Transplant
MUSC Health Charleston, SC
Job Description Summary Main 6E Transplant is a dynamic 22-bed adult inpatient unit dedicated to caring for fresh post-operative solid organ abdominal transplant patients. Our nurses play a vital role in supporting kidney, liver, and kidney/pancreas transplant recipients through every stage of their journey, from pre-transplant preparation to post-transplant recovery. Work in both Intermediate/Stepdown and Acute Care settings, allowing you to broaden and strengthen your clinical skills. Intermediate Care nurses manage highly specialized patients with arterial lines and advanced drips. We invest in your success. All nurses become ACLS certified and trained in peritoneal dialysis within the first six months, building a strong clinical foundation that opens doors across the organization. While transplant is our core specialty, MH6E cares for a wide range of acute care patients, giving nurses continuous opportunities to learn and refine their practice. If you’re looking for a...

Jun 10, 2026
MUSC Health
Full time, Full Time
 
UNIV - Registered Nurse III - Department of SCTR
MUSC Health Charleston, SC
Job Description Summary Serve as a Research Nurse providing a wide range of technical, clinical and professional services within the SCTR Nexus Clinical Research Unit and satellite locations. Serve as preceptor for new staff and provide leadership to the unit for daily operations. Chemotherapy infusion knowledge and experience preferred. Strong phlebotomy and IV insertion skills required. Entity Medical University of South Carolina (MUSC - Univ) Worker Type Employee Worker Sub-Type​ Research Grant Cost Center CC001064 COM SCTR Operations CC Pay Rate Type Hourly Pay Grade University-08 Pay Range 69,764.00 - 99,421.00 - 129,077.000 Scheduled Weekly Hours 40 Work Shift Job Description Serve as a Research Nurse providing a wide range of technical, clinical and professional services within the SCTR Nexus Clinical Research Unit and satellite locations. Serve as preceptor for new staff and provide leadership to the unit for daily operations....

Jun 10, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse I (New Graduate) - 6W Specialty Medicine and Acute Care
MUSC Health Charleston, SC
Job Description Summary Main 6 West is a 15-bed Specialty Medicine & Acute Care unit where no two days are ever the same! We care for adult patients with complex liver disease and a wide range of acute medical conditions. Our nurses play an important role in supporting patients with acute kidney injury, liver failure, cirrhosis, and those preparing for or recovering from a liver transplant along with many other specialty medical conditions. We are committed to professional growth and clinical excellence. Nurses on 6 West build a strong foundation in specialty medicine while refining time management, prioritization, and critical thinking skills that translate across multiple practice settings. The diversity and acuity of our patient population ensure continuous learning and ongoing opportunities to expand clinical expertise If you are looking for a supportive, team focused environment where you can grow your skills, build meaningful patient relationships, and make a real...

Jun 10, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse - MUSC Health Atlantic Cardiovascular Associates - MUSCP
MUSC Health Ladson, SC
Job Description Summary Join our dynamic team at MUSC Health Atlantic Cardiovascular Associates, a new MUSC physician office offering general and interventional cardiology care. Our team thrives on mutual support and respect, working together to make a real difference in our patients' lives. If you're passionate about healthcare and eager to be part of a team that values professional growth and compassionate care, we’d love to have you with us! Under general supervision, the Registered Nurse I provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Responsible for providing quality nursing care while maintaining accountability for the coordination of patient care. Entity Carolina Family Care, Inc. (CFC) Worker Type Employee Worker Sub-Type​...

Jun 22, 2026
Roper St. Francis Healthcare
Registered Nurse (RN) Clinical Specialist — Oncology & Bone Marrow Transplant — Roper Hospital
Roper St. Francis Healthcare Charleston, SC
ROPRSFUSR278994EXTERNALENUS Thank you for considering a career at Roper St. Francis Healthcare! LOCATION: ROPER HOSPITAL - Downtown Charleston HOURS: 7:30am - 4:00pm *THIS IS NOT A REMOTE POSITION* **Prefer recent clinical experience, Oncology experience highly preferred** Job Summary: The RN Clinical Specialist exhibits current clinical knowledge and expertise for designated patient populations and is accountable for continued competence in nursing practice and clinical outcomes in accordance with current evidenced – based practice guidelines. Responsible for facilitating the planning, implementation and evaluation of the process-improvement initiatives to promote excellence, insure patient and staff safety, and enhance quality of care. Assumes leadership role in departmental and organizational goals. Facilitates on-going peer review and mentoring programs. Job Summary Specific to GI Services (Digestive Health and Continence): Utilizes the...

Jul 04, 2026
Roper St. Francis Healthcare
PRN
 
Registered Nurse (RN) Care Manager — Roper Hospital — PRN
Roper St. Francis Healthcare Charleston, SC
ROPRSFUSR278399EXTERNALENUS Thank you for considering a career at Roper St. Francis Healthcare! Primary Function/General Purpose of Position The RN Care Manager is responsible for providing coordination of care for patients to support safe, seamless, timely transitions across the continuum. This role utilizes a collaborative process, the RN Care Manager identifies (using quantitative and qualitative methods), assesses, plans, implements and evaluates the options and services required to meet an individual’s health and health related needs, including social- determinants that affect ones’ overall wellbeing. The RN Care Manager is responsible for screening, identification, and assessment of individuals in need of active Case Management services and promotes the right resources, at the right time and at the right place. Essential Job Functions Identifies and prioritizes patients in need of care management services, using a holistic approach inclusive of biopsychosocial,...

Jul 01, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Peds Heart Center
MUSC Health Charleston, SC
Job Description Summary Peds Heart Center is a 29-bed unit- ranked #4 Nationally by U.S News and World Report and #1 in patient outcomes, in addition to being a AACN Beacon Award-Winning unit. We are the referral center for all major pediatric cardiac surgery in South Carolina. Average Daily Census on the unit is 28, with a blend of cardiac surgical and medical diagnoses. The Heart Center cares for patients with congenital and acute heart disease of any age based on care needs. Common procedures associated with this unit's care include cardiac surgery, Ventricular Assist Devices, Heart Transplant, cardiac catheterization, and all medical diagnoses associated with cardiac care for the children in South Carolina. In addition to ventilatory and cardiac support, the unit provides ECMO/CRRT and additional complex supportive therapies. Pediatric palliative care is available as needed. The staffing mix includes Registered Nurses, Patient Care Technicians, and Unit Secretaries with...

Jun 29, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - ART 7E Oncology
MUSC Health Charleston, SC
Job Description Summary ART 7 East is a dynamic 19-bed unit dedicated to the care of adult oncology and medical-surgical patients. The team expertly manages complex cancer diagnoses, including both hematologic malignancies and solid organ tumors, and provides specialized care for patients receiving high-risk chemotherapy, immunotherapy, and those enrolled in clinical trials. The unit also addresses treatment-related side effects with close monitoring and individualized interventions. In addition to oncology patients, ART 7 East cares for a diverse medical-surgical population ranging from moderate to high acuity, offering a challenging and rewarding clinical environment. All nurses are required to complete the National Cancer Institute Collaborative Systemic Therapies Course within their first year to achieve chemotherapy competency, with ongoing opportunities for advanced, cancer-specific education. The unit strongly encourages specialty certification in oncology,...

Jun 29, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Adult Cardiac Cath Lab
MUSC Health Charleston, SC
Job Description Summary The RN CVP II is able to competently perform all aspects of care (sedating, monitoring, scrubbing, and circulating) during Diagnostic / Interventional Cardiac Procedures and EP procedures (Excluding: Complex Ablation cases). The MUSC Cardiac Cath Lab consists of five state-of-the-art labs plus one hybrid OR supported by a Prep and Recovery unit. We provide advanced cardiac catheterization care for heart attack, stroke and coronary artery disease, including chronic total coronary occlusion. We continue to expand our Heart Failure program and are the largest transplant facility in South Carolina. MUSC Health also offers more treatment options for heart valve disease than any other center in the state, including minimally invasive TAVR, TAVI, TEER, TMVR & MitraClip approaches. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000305 CHS - Cardio Cath - Adult (ART) Pay Rate...

Jun 22, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse I or II - Endocrinology/Infectious Disease Clinic
MUSC Health Charleston, SC
Job Description Summary RN I Job Summary/Purpose: Under general supervision, the Registered Nurse I (New Graduate) assists at the advanced beginner level in providing individualized, goal directed nursing care to patients and families utilizing principles and practices of the nursing process; interacts with other members of the health care team to achieve desired outcomes. RN II Job Summary/Purpose: Under general supervision, the Registered Nurse II provides individualized, goal-directed patient care to families and patients at the competent level utilizing the principles and practices of the nursing process; delivers safe and effective care and interacts with other members of the health care team to achieve desired results. Role involves intake/triage and rooming for clinic visits and utilization of nursing skills including nursing assessment, administration of first dose IV and IM antibiotics, PICC line maintenance and/or removal, STIM tests, among other nursing tasks. You...

Jun 22, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Adult Critical Care - Float Team
MUSC Health Charleston, SC
Job Description Summary Meduflex is MUSC Charleston’s inpatient Float Pool, supporting a wide range of patient care units across the downtown campus. Spanning 10 specialized zones and serving both Adult and Pediatric populations, the team offers Registered Nurses (RNs) flexible scheduling and additional float differential pay. This particular role is within the Adult Critical Care Zone, where you'll provide care across several high-acuity units—including the Surgical Trauma Burn ICU, Cardiac ICUs, and both Medical and Surgical ICUs—with occasional floating to Intermediate Care units in the Main Hospital and Ashley River Tower, based on staffing needs. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000517 CHS - Meduflex Team (Main) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Rotating (United States of America) Job Description Hours...

Jun 15, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Adult Acute Care - Float Team
MUSC Health Charleston, SC
Job Description Summary Meduflex is MUSC Charleston’s inpatient Float Pool, supporting a wide range of patient care units across the downtown campus. Spanning 10 specialized zones and serving both Adult and Pediatric populations, the team offers Registered Nurses (RNs) flexible scheduling and additional float differential pay. In this diverse and fast-paced zone, you’ll have the exciting opportunity to float between specialized units—including Cardiac, Gastrointestinal, Neurology, Transplant, Oncology, and General Medical and Surgical floors—across both Main Hospital and Ashley River Tower. This role offers a unique chance to broaden your clinical skills, work with a variety of patient populations, and make a meaningful impact in multiple areas of care. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000517 CHS - Meduflex Team (Main) Pay Rate Type Hourly Pay Grade Health-28 Scheduled...

Jun 15, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Labor & Delivery - Float Team
MUSC Health Charleston, SC
Job Description Summary Meduflex is MUSC Charleston’s inpatient Float Pool, supporting a wide range of patient care units across the downtown campus. Spanning 10 specialized zones and serving both Adult and Pediatric populations, the team offers Registered Nurses (RNs) flexible scheduling and additional float differential pay. In this versatile role, you’ll have the rewarding opportunity to float between the Antepartum unit and Labor and Delivery, providing personalized, compassionate care to expectant mothers—whether they are preparing for delivery or experiencing early labor. This role offers a dynamic and supportive environment where you can make a real difference during such an important time in your patients’ lives. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000517 CHS - Meduflex Team (Main) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Nights...

Jun 15, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Peds Critical Care - Float Team
MUSC Health Charleston, SC
Job Description Summary The Float Team serves adult and pediatric populations across 10 specialized zones. This RN position on the Float Team offers flexible scheduling, float differential pay, and an optional $30,000 sign-on bonus for full-time external candidates with two or more years of pediatric critical care experience (three-year service agreement required). In this pediatric-focused role, nurses float between the PICU, PCICU, and NICU, with additional support opportunities throughout Shawn Jenkins Children’s Hospital, creating a dynamic and rewarding nursing experience. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000517 CHS - Meduflex Team (Main) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Rotating (United States of America) Job Description Hours per week: Vary based on preference, Rotating (waitlist for days) .6 FTE: 2-12 hour...

Jun 15, 2026
MUSC Health
Full time, Full Time
 
Registered Nurse II - Peds Acute Care - Float Team
MUSC Health Charleston, SC
Job Description Summary The Float Team serves adult and pediatric populations across 10 specialized zones. This RN position on the Float Team offers flexible scheduling, float differential pay, and an optional $15,000 sign-on bonus for full-time external candidates with two or more years of pediatric acute care experience (two-year service agreement required). In this role, you’ll deliver high-quality, compassionate care across specialized pediatric units including Pediatric Acute Care, Oncology, Cardiac Intermediate, and the NICU, caring for up to Level 2 patients. You may also support intermediate-level care in the Pediatric ICUs at Shawn Jenkins Children’s Hospital as needed. Entity Medical University Hospital Authority (MUHA) Worker Type Employee Worker Sub-Type​ Regular Cost Center CC000517 CHS - Meduflex Team (Main) Pay Rate Type Hourly Pay Grade Health-28 Scheduled Weekly Hours 36 Work Shift Nights (United States of America) Job...

Jun 15, 2026
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